Carcinogenesis, Teratogenesis & Mutagenesis ›› 2002, Vol. 14 ›› Issue (2): 118-120.doi: 10.3969/j.issn.1004-616x.2002.02.015

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STUDY ON THE GENOTOXICITY OF GANTAIKANG

LIU Xiu-ying; HU Yi-xiu; QIU Feng, HU Yu-ming; ZANG Xue-bing; ZHOU Yue-chan   

  1. Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
  • Received:2001-09-25 Revised:2001-11-15 Online:2002-04-30 Published:2002-04-30
  • Contact: LIU Xiu-ying

Abstract: Purpose and Methods : The genotoxic activity of Gantaikang was studied by Ames test , micronucle-us test of polychromatic erythrocytes in bone marrow and sperm shape abnormality test in mice to provide the data basis for it's safety. Results and Conclusion : The results of the three test s were all negative , which suggested that Gantaikang is not mutagenic to tested strains , somatic cells and male germ cells in mice.

Key words: Gantaikang, Ames test, micronucleus test, sperm shape abnormality test